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In - House Oral Medications Levothyroxine 100 Mcg Tablet Treat Hypothyroidism

Categories Oral Medications
Brand Name: Newlystar
Place of Origin: China
MOQ: 500, 000 tablets
Payment Terms: L/C, T/T
Delivery Time: 45days
Packaging Details: 10’s/blister
Model Number: 50mcg, 100mcg
Certification: GMP
Price: Negotiation
Supply Ability: one million pills per day
Product: Levothyroxine Tablets
Specification: 50mcg, 100mcg
Standard: In - house
Packing: 10’s/blister
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    In - House Oral Medications Levothyroxine 100 Mcg Tablet Treat Hypothyroidism

    In - House Oral Medications Levothyroxine 100 Mcg Tablet Treat Hypothyroidism


    Product : Levothyroxine Tablets

    Specification : 50mcg, 100mcg

    Standard : In - house

    Packing : 10’s/blister


    Description :

    Levothyroxine is a major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum of stimulatory effects on cell metabolism.


    Indication

    For use alone or in combination with antithyroid agents to treat hypothyroidism, goiter, chronic lymphocytic thyroiditis, myxedema coma, and stupor.


    Pharmacodynamics

    Levothyroxine (T4) is a synthetically prepared levo isomer of thyroxine, the major hormone secreted from the thyroid gland. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine (T3) which exerts a broad spectrum of stimulatory effects on cell metabolism. Thyroid hormone increases the metabolic rate of cells of all tissues in the body. In the fetus and newborn, thyroid hormone is important for the growth and development of all tissues including bones and the brain. In adults, thyroid hormone helps to maintain brain function, food metabolism, and body temperature, among other effects. The symptoms of thyroid deficiency relieved by levothyroxine include slow speech, lack of energy, weight gain, hair loss, dry thick skin and unusual sensitivity to cold.


    Mechanism of action

    Levothyroxine acts like the endogenous thyroid hormone thyroxine (T4, a tetra-iodinated tyrosine derivative). In the liver and kidney, T4 is converted to T3, the active metabolite. In order to increase solubility, the thyroid hormones attach to thyroid hormone binding proteins, thyroxin-binding globulin, and thyroxin-binding prealbumin (transthyretin). Transport and binding to thyroid hormone receptors in the cytoplasm and nucleus then takes place. Thus by acting as a replacement for natural thyroxine, symptoms of thyroxine deficiency are relieved.

    Product Tags:

    Oral Preparation

      

    oral treatment

      
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