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Ganoderma lucidum (Leysser.Fr)Karst

Country/Region china
Company Gentcare Natural Ingredients Inc
Categories Health Food
Telephone +86-731-8228 7663, +86 139 0748 7460
ICP License Issued by the Chinese Ministry
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    Ganoderma lucidum (Leysser.Fr)Karst


    Brief Introduction
    Synonyms
    ---Lingzhi Mushroom (Chinese: ), Ganodema lucidum Mushroom, Mannentake(Japanese: )

    Beta-Glucan
    Chemical Name: Beta-Glucan, Beta-D-Glucan, Beta-(1,3)-D-Glucan
    Molecular Formula: C18H30O14X2
    Mol. Wt.: 470.42
    Molecular Structure::
     
    Triterpenes(Ganoderic acids)
    Chemical Name: Triterpenes, Triterpene saponins, Ganoderic acid A( a compound isolated from the Reishi mushroom)
    Cas No.: 81907-62-2
    Molecular Formula: C30H44O7
    Mol. Wt.: 516.67
    Molecular Structure::
    Reishi mushroom (Chinese: Lngzh, traditional Chinese: ; simplified Chinese: ; Japanese: reishi; Korean: yeongji) is the name for one form of the mushroom Ganoderma lucidum, and its close relative Ganoderma tsugae. Ganoderma lucidum enjoys special veneration in Asia, where it has been used as a medicinal mushroom in traditional Chinese medicine for more than 4,000 years, making it one of the oldest mushrooms known to have been used in medicine.
    The word lingzhi, in Chinese, means "herb of spiritual potency" and has also been described as "mushroom of immortality". Because of its presumed health benefits and apparent absence of side-effects, it has attained a reputation in the East as the ultimate herbal substance. Lingzhi is listed in the American Herbal Pharmacopoeia and Therapeutic Compendium.
    Ganoderma lucidum produces a group of triterpenes, called ganoderic acids, which have a molecular structure similar to steroid hormones. It also contains other compounds many of which are typically found in fungal materials, such as Maitake, Shitake, Agaricus blazei, Agaricus biporus, including polysaccharides such as beta-glucan, coumarin, mannitol, and alkaloids.
    Ganoderic acids are a class of closely related triterpenes found in Ganoderma mushrooms. For thousands of years, the fruiting bodies of Ganoderma fungi have been used in traditional medicines in East Asia. Consequently, there have been efforts to identify the chemical constituents that may be responsible for the putative pharmacological effects. There are dozens of ganoderic acids that have been isolated and characterized, of which ganoderic acid A and ganoderic acid B are the best characterized. Some ganoderic acids have been found to possess biological activities including hepatoprotection, anti-tumor effects, and 5-alpha reductase inhibition.
    The Reishi Mushroom Extract used in dietary supplements is derived from the whole mushroom (the fruiting bodies of Ganodema fungi). The red Reishi Mushroom is better than the black Reishi Mushroom, and the former taste more bitter than the latter.
    Benefits

    Reishi Mushroom contains a high concentration of beta-glucan and Granoderic acids (Triterpenes), compounds which has been shown to stimulate immune system and anti-tumor:
    Up-regulate the immune system (Immunomodulatory and immunotherapeutic activities)
    Anti-cancer, anti-tumor, and anti-neoplastic effects
    Prevent cancer metastasis
    Anti-bacterial and anti-viral activities
    Beneficial effect on Lowering Blood Pressure(via inhibition of angiotensin-converting enzyme)
    Beneficial effect on Lowering Blood Sugar
    Beneficial effect on Lowering Cholesterol
    Protective effects against liver injury by viruses and other toxic agents
    Weight loss aid
    Mechanism

    Beta-glucan and the immune system
    Beta-glucans are known as "biological response modifiers" because of their ability to activate the immune system. Immunologists at the University of Louisville, discovered that a receptor on the surface of innate immune cells called Complement Receptor 3 (CR3 or CD11b/CD18) is responsible for binding to beta-glucans, allowing the immune cells to recognize them as "non-self." However, it should be noted that the activity of beta-glucans is different from some pharmaceutical drugs which have the ability to over-stimulate the immune system. Pharmaceutical drugs have the potential to push the immune system to over-stimulation, and hence are contraindicated in individuals with autoimmune diseases, allergies, or yeast infections. Beta-glucans seem to make the immune system work better without becoming overactive. In addition to enhancing the activity of the immune system, beta-glucans also reportedly lower elevate

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